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UNICEF's mission is to help very child thrive, all over the world. Over eight decades, it has built an unprecedented global support system for the world’s children. UNICEF relentlessly works day in and day out to deliver the essentials that give every child an equitable chance in life: health care and immunizations, safe water and sanitation, nutrition, education, emergency relief and more. UNICEF USA advances the global mission of UNICEF by rallying the American public to support the world’s most vulnerable children. Through advocacy, education and fundraising in the United States. The organization's Impact Fund for Children provides opportunities for social impact investors seeking to make a difference in the survival and development of children.

GlobalGiving makes it possible for anyone to give to community-led nonprofits all over the world. Our mission is to transform aid and philanthropy to accelerate community-led change. We make it possible for you to support local projects in 170 countries, giving nonprofits access to the funding, tools, and training they need to become more effective and to make our world a better place.

Global Empowerment Mission (GEM) acts as a first responder to vulnerable communities affected by disasters around the world. GEM is dedicated to restoring hope and opportunity in the lives of those most affected by disasters. The organization provides immediate relief, assists communities during the gap period before receiving assistance from other institutions, and engages in long-term recovery efforts with sustainable development practices. This three-phased approach allows GEM to provide individuals and families with the help they need when they need it most.

The Salvation Army, an international movement, is an evangelical part of the universal Christian Church. Its message is based on the Bible. Its ministry is motivated by the love of God. Its mission is to preach the gospel of Jesus Christ and to meet human needs in His name without discrimination.

The International Rescue Committee responds to the world's worst humanitarian crises, helping to restore health, safety, education, economic wellbeing, and power to people devastated by conflict and disaster. Founded in 1933 at the call of Albert Einstein, the IRC is at work in over 50 countries and more than 20 U.S. cities helping people to survive, reclaim control of their future and strengthen their communities. Over the past 90 years, the IRC has built a strong position as the largest refugee resettlement agency in the United States, and has paid close attention and provided service to the recent conflicts in Afghanistan (providing education and protection to 1 million Afghan citizens including women and girls) and Ukraine (collaborating with nonprofit organizations in both Ukraine and refugee-receiving Poland to provide aid).

As the world's leading independent organization for children in need, Save the Children has programs in nearly 120 countries, including the United States. Their aim is to inspire breakthroughs in the way the world treats children, and to create immediate and lasting change in their lives by improving their health, education and economic opportunities. In times of acute crisis, Save the Children mobilizes rapid assistance to help children recover from the effects of war, conflict and natural disasters.

City of Hope, an innovative biomedical research, treatment and educational institution, is dedicated to the prevention and cure of cancer and other life-threatening diseases, guided by a compassionate, patient-centered philosophy and supported by a national foundation of humanitarian philanthropy. City of Hope is dedicated to making a difference in the lives of people with cancer, diabetes and other serious illnesses. Our mission is to transform the future of health care by turning science into a practical benefit, hope into reality. We accomplish this by providing outstanding care, conducting innovative research and offering vital education programs focused on eliminating these diseases. Founded in 1913, City of Hope is one of only 41 comprehensive cancer centers in the nation, as designated by the National Cancer Institute. Our role as leaders in patient care, basic and clinical research, and the translation of science into tangible benefit is widely acknowledged. Our community includes research associates, scientists, doctors, nurses, allied health professionals, graduate students, fundraising specialists, marketing professionals, volunteers and an extensive support staff. We are united by our desire to find cures, save lives and transform the future of health. Every discovery we make and every new treatment we create gives people the chance to live longer, better and more fully. City of Hope continues to be a pioneer of patient centered care and remains committed to its tradition of exceptional care for patients, families and communities. Each day, we live out our credo: "There is no profit in curing the body, if, in the process, we destroy the soul."

The American Cancer Society’s mission is to improve the lives of people with cancer and their families through advocacy, research, and patient support , to ensure everyone has an opportunity to prevent, find, treat, and survive cancer.

The American Foundation for Suicide Prevention is dedicated to saving lives and bringing hope to those affected by suicide. AFSP creates a culture that’s smart about mental health through education and community programs, develops suicide prevention through research and advocacy, and provides support for those affected by suicide. AFSP has local chapters in all 50 states with programs and events nationwide.

The Palestine Children's Relief Fund (PCRF) is a non-political, non-profit organization dedicated to healing the wounds of war, occupation and poverty for children in the Middle East, regardless of their nationality, religion, race or gender.

We are a nonprofit agency that promotes justice by providing free and low-cost legal services to under served immigrant children, families, and refugees. With legal services, social programs, bond assistance, and an advocacy team focused on changing the narrative around immigration in this country, RAICES is operating on the national front lines of the fight for immigration rights. We defend the rights of immigrants and refugees, empower individuals, families, and communities, and advocate for liberty and justice. Since 2018, our Bond Fund is the largest in the nation with just under $12 million spent to secure the release of more than 1,200 individuals from ICE detention. Our San Antonio Bus Station Project helped more than 9,000 adults and 12,000 children released from detention understand their legal rights. We have a volunteer program with over 5,000 trained volunteers and pro bono lawyers to perform essential tasks such as accompanying people to ICE check-ins and preparing detained clients for credible fear interviews.

WWF's mission is the conservation of nature. Using the best available scientific knowledge and advancing that knowledge where we can, we work to preserve the diversity and abundance of life on Earth and the health of ecological systems by protecting natural areas and wild populations of plants and animals, including endangered species; promoting sustainable approaches to the use of renewable natural resources; and promoting more efficient use of resources and energy and the maximum reduction of pollution. We are committed to reversing the degradation of our planet's natural environment and to building a future in which human needs are met in harmony with nature. We recognize the critical relevance of human numbers, poverty and consumption patterns to meeting these goals.