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UNICEF's mission is to help very child thrive, all over the world. Over eight decades, it has built an unprecedented global support system for the world’s children. UNICEF relentlessly works day in and day out to deliver the essentials that give every child an equitable chance in life: health care and immunizations, safe water and sanitation, nutrition, education, emergency relief and more. UNICEF USA advances the global mission of UNICEF by rallying the American public to support the world’s most vulnerable children. Through advocacy, education and fundraising in the United States. The organization's Impact Fund for Children provides opportunities for social impact investors seeking to make a difference in the survival and development of children.

charity: water is a non-profit organization bringing clean and safe drinking water to people in developing nations. We inspire giving and empower others to fundraise for sustainable water solutions. We use local partners on the ground to build and implement the projects. Then, we prove every single project funded, using GPS coordinates, photos and stories from the field. We have funded 91, 414 water projects, aimed to serve 14, 762, 215 people in 29 countries. We believe that sustainable work is locally-led. Along with implementing community-owned water projects, our local partners help facilitate comprehensive water, sanitation, and hygiene (WASH) programming to protect everyone’s long-term health.

The Leukemia and Lymphoma Society (LLS) is a global leader in the fight against cancer. The LLS mission: Cure leukemia, lymphoma, Hodgkin's disease and myeloma, and improve the quality of life of patients and their families. We are the largest nonprofit dedicated to creating a world without blood cancers. Since 1949, we've invested more than $1.6 billion in groundbreaking research, pioneering many of today's most innovative approaches. LLS provides free information and support services for patients, survivors, families and healthcare professionals, and is the voice for all blood cancer patients seeking access to quality, affordable, coordinated care through an advocacy network of over 100,000 volunteers at the state and federal level.

Direct Relief improves the health and lives of people affected by poverty or emergency situations by mobilizing and providing essential medical resources needed for their care. Direct Relief works in all 50 U.S. states and in more than 90 countries to expand access to medicine and healthcare by equipping doctors and nurses with lifesaving medical resources.

As the world's leading independent organization for children in need, Save the Children has programs in nearly 120 countries, including the United States. Their aim is to inspire breakthroughs in the way the world treats children, and to create immediate and lasting change in their lives by improving their health, education and economic opportunities. In times of acute crisis, Save the Children mobilizes rapid assistance to help children recover from the effects of war, conflict and natural disasters.

Crisis Text Line provides free, 24/7, high-quality text-based mental health support and crisis intervention by empowering a community of trained volunteers to support people in their moments of need.

The Foundation's goal is to provide the ultimate environment for a child to become their best in all areas of their life, including academic, athletic, interpersonal skills, leadership, as a mentor, and someone willing to be mentored. They hope to arm children with a variety of ways to grow intellectually, spiritually, physically, and in their relationships with themselves and others. Their program is designed to go deeper into the subjects of life, excellence, and how to pursue happiness. In the end, our long-term goal is to help them become professionals in life, to find peace of mind, so they can share this wisdom with their families, friends, and communities as leaders and examples of extraordinary living and happiness.

The mission of Doctors Without Borders/Médecins Sans Frontières (MSF) is to provide impartial medical relief to the victims of war, disease, and natural or man-made disaster, without regard to race, religion, or political affiliation. A non-profit, self-governed, member-based organisation, MSF's global reach is demonstrated by a presence in over 72 countries and territories with medical humanitarian projects, 9,904,200 medical consultations conducted by humanitarian teams, and 877,300 patients admitted to MSF hospitals or clinics around the world.

The Trevor Project is the world’s largest suicide prevention and crisis intervention organization for LGBTQ+ (lesbian, gay, bisexual, transgender, queer, and questioning) young people. The organization works to save young lives by providing support through free and confidential suicide prevention and crisis intervention programs on platforms where young people spend their time: a 24/7 phone lifeline, chat, and text. The organization also runs TrevorSpace, the world’s largest safe space social networking site for LGBTQ youth, and operates innovative education, research, and advocacy programs.

Nancy G. Brinker promised her sister that she would do everything in her power to end breast cancer forever. That promise is now Susan G. Komen for the Cure®, the global leader of the breast cancer movement, having invested more than $2.2 billion since inception in 1982. As the world’s largest grassroots network of breast cancer survivors and activists, we’re working together to save lives, empower people, ensure quality care for all and energize science to find the cures. Thanks to events like the Susan G. Komen Race for the Cure® and the Susan G. Komen 3-Day for the Cure®, and generous contributions from our partners, sponsors and fellow supporters, we have become the largest source of nonprofit funds dedicated to the fight against breast cancer in the world.

The mission of the American Diabetes Association (the Association) is to prevent and cure diabetes and to improve the lives of all people affected by diabetes. Diabetes is a disease in which the body does not produce or properly use insulin.  Insulin is a hormone that is needed to convert sugar, starches and other food into energy needed for daily life.  The cause of diabetes continues to elude the medical community, although research has shown that both genetics and environmental factors such as obesity and lack of exercise appear to play roles.

City of Hope, an innovative biomedical research, treatment and educational institution, is dedicated to the prevention and cure of cancer and other life-threatening diseases, guided by a compassionate, patient-centered philosophy and supported by a national foundation of humanitarian philanthropy. City of Hope is dedicated to making a difference in the lives of people with cancer, diabetes and other serious illnesses. Our mission is to transform the future of health care by turning science into a practical benefit, hope into reality. We accomplish this by providing outstanding care, conducting innovative research and offering vital education programs focused on eliminating these diseases. Founded in 1913, City of Hope is one of only 41 comprehensive cancer centers in the nation, as designated by the National Cancer Institute. Our role as leaders in patient care, basic and clinical research, and the translation of science into tangible benefit is widely acknowledged. Our community includes research associates, scientists, doctors, nurses, allied health professionals, graduate students, fundraising specialists, marketing professionals, volunteers and an extensive support staff. We are united by our desire to find cures, save lives and transform the future of health. Every discovery we make and every new treatment we create gives people the chance to live longer, better and more fully. City of Hope continues to be a pioneer of patient centered care and remains committed to its tradition of exceptional care for patients, families and communities. Each day, we live out our credo: "There is no profit in curing the body, if, in the process, we destroy the soul."